Heteromeric nature of glucocorticoid receptor

the nature of acetylcholine receptor

the present work with consideratlon to the autoradiographic pictures, suggests that cholinergic receptors are located at the gate of a channel originating from synaptic cleft coming to lie within the muscle fibre. ache molecules stand at the gate of this channel,controlling the entrance of different cholinergic agents. it was report- ••• ed previously that dtc molecules s t.abd ;:.2e the ache r...

Specific Signaling Through Heteromeric PDGF Receptor Complexes

Ekman, S. 2000. Specific signaling through heteromeric PDGF receptor complexes. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 947. 80pp. Uppsala. ISBN 91-554-4785-6 Platelet-derived growth factor (PDGF) is a potent mitogen and chemoattractant for mesenchymal cells and exert its effect by binding to two structurally related receptor...

The glucocorticoid receptor.

The glucocorticoid receptor resource

The glucocorticoid receptor resource focuses on the structure-function relationships of the glucocorticoid receptor. As well as links to sequence and bibliographic databases via the World Wide Web, the database contains sequence comparisons of receptors from different species and source information for glucocorticoid receptor clones, probes, cell lines and antibodies. The resource allows the el...

Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis

The mechanisms by which glucocorticoid receptor (GR) mediates glucocorticoid (GC)-induced apoptosis are unknown. We studied the role of mitochondrial GR in this process. Dexamethasone induces GR translocation to the mitochondria in GC-sensitive, but not in GC-resistant, T cell lines. In contrast, nuclear GR translocation occurs in all cell types. Thymic epithelial cells, which cause apoptosis o...